Oncology
A global solution, from sample to result
Based on its expertise in molecular biology, from nucleic acid extraction to digital PCR, ID SOLUTIONS develops and offers a range of products dedicated to oncology.
ID SOLUTIONS ONCOLOGY kits:
- Based on dPCR : detection of several molecular alterations in a single well
- Incorporate sample qualification and/or quantification controls.
- ICE = Internal Control of Extraction: patent FR3061720/ WO2018…
- Suitable for analysis of free circulating DNA or tissue DNA
- Offer sensitive, specific, standardizedresults to meet today’s needs and requirements.
ID SOLUTIONS ONCOLOGY kits provide :
Qualification and/or quantification of each sample
Normalization of circulating DNA concentration
Detection of cancer-specific mutations
IDESR1
Detection system for ESR1 activating mutations on Exon 8 and the E380Q mutation
- ESR1
- 25 tests
IDEGFR-SENSI
Multiplex EGFR mutation detection system (L858R, L861Q, Del19)
- EGFR
- 50 tests
IDEGFR-RESIST
Multiplex EGFR mutation detection system (T790M, C797S)
- EGFR
- 50 tests
IDEGFR-RARE
Multiplex EGFR mutation detection system (S768I, G719X, ins20)
- EGFR
- 50 tests
IDKRAS
Multiplex KRAS mutation detection system (G12-G13, Q61)
- KRAS
- 50 tests
IDKRAS-3X
Multiplex system for detecting mutations in exon 2 (variants G12X and G13X), exon 3 (variants Q61X) and exon 4 (variants A146X and K117)
- KRAS
- 50 tests
IDKRAS-G12C
Multiplex KRAS mutation detection system (G12C)
- KRAS
- 50 tests
IDNRAS
Multiplex NRAS mutation detection system (G12-G13, Q61)
- NRAS
- 50 tests
IDBRAF
Multiplex BRAF mutation detection system (L597, A598, V600, K601)
- BRAF
- 50 tests
IDBRAF-CNS
Multiplex detection system for BRAF V600E mutation and KIAA1546-BRAF fusion
- BRAF
- 25 tests
IDPIK3CA
Multiplex detection system for PIK3CA mutations (E542/5K, H1057R/L, Q546K)
- PIK3CA
- 25 tests
IDIDH1-2
Multiplex IDH1-2 mutation detection system (R132X, R172X)
- IDH1-2
- 25 tests
IDIDH1-2 + R140X
Multiplex IDH1-2 mutation detection system (R132X, R172X, R140X)
- IDH1-2
- 25 tests
IDH3F3A
Multiplex detection system for H3F3A mutations (K27M, G34V, G34R)
- H3F3A
- 25 tests
IDTERT
Multiplex TERT mutation detection system (C228T, C250T)
- TERT
- 25 tests
IDFGFR1-CNS
Multiplex detection system for FGFR1 mutations and tandem duplication of exons 11 to 18
- FGFR1
- 25 tests
IDmMLH1
Multiplex detection system for FGFR1 mutations and tandem duplication of exons 11 to 18
- MLH1
- 25 tests
Multiplexed solutions / Quality control / Validation data Validation data
Speed
Results in less 24h
Ready to use
Suitable for FFPE and plasma samples
High specificity and sensitivity
Up to 1% in FFPE and 0.1% in plasma
Quality controls included
Standardization and normalization of results
High compatibility
Compatible with market-leading dPCR instruments
A simplified digital PCR workflow
Only when using research reagents
Extraction
Step 1:
DNA isolation from tissue or plasma*
Qualification quantification
Step 2:
Standardization*
Deposit
Step 3:
Sample + Mix*
Partition
Step 4:
DNA partitioning
Amplification
Step 5:
Amplification and detection
Analysis
Step 6:
Results analysis
*Possible automation
DNA extraction kits optimized for plasma and FFPE samples
A solution for your tumor DNA extractions
Enhance your pre-analytical steps and qualify your extraction by adding controls:
– Positive extraction control, treated as a sample
to validate each extraction
– Internal extraction control, distributed in each sample to
standardize extraction
Official publication numbers of “FR3061720” / “WO2018/127674” applications
IDQUANT, kit for quantifying and normalizing circulating DNA by qPCR or digital PCR (dPCR)
The IDQUANT kit enables standardized monitoring of circulating DNA over time, thanks to our internal control (ICE).
The kit contains a Target Positive Control (TPC) for validation from extraction to amplification.
Sample qualification / Standardized quantification
